The Effect of Oral Hyaluronic Acid on Skin Aging

Hyaluronic acid is a polysaccharide found in the skin, and it plays a significant role in maintaining moisture content and promoting tissue repair. However, hyaluronic acid content decreases with aging, contributing heavily to wrinkles and general dehydration.

While hyaluronic acid is a common component in topical skincare products, a study examined the effect of oral hyaluronic on reduction in signs of skin aging.

The study lasted for 28 days and consisted of 60 women aged 35 to 70 with signs of aging ranging from mild to moderate. Participants were randomly assigned 200 mg of hyaluronic acid or a placebo daily. To determine the results, outcomes measured include wrinkle depth, wrinkle volume, skin hydration, trans-epidermal water loss (TEWL), skin elasticity, skin firmness, and blood levels of hyaluronic acid.

When compared to participants given a placebo, those who ingested 200 mg of hyaluronic acid daily had reduced wrinkle depth, wrinkle volume, and TEWL while skin hydration and elasticity increased. These results support the benefits of oral hyaluronic acid for reducing the signs of aging on the skin, providing yet another method to combat the visible signs of aging.